Clinical Outcomes · Portland, OR

When six medications weren't enough,
the data said try this.

Ketamine infusion therapy for treatment-resistant depression, PTSD, and chronic pain — administered in a space that feels nothing like a hospital.

83%
Response rate in treatment-resistant patients
Based on 2,400+ infusions administered at Infuse, 2021–2025
4.2
Average sessions to sustained remission
Median across PHQ-9 assessments; individual results vary
2,400+
Infusions administered since opening
Tracked across all patient cohorts, verified by clinical records
Patient Stories
Patient Outcomes
"I had tried every antidepressant my psychiatrist could prescribe. After my third infusion, I woke up and the weight was just... gone. Not dulled. Gone."
Margaret T. · Treatment-resistant MDD, 12 years · 6 infusions
David R.
Treatment-Resistant Depression
6 sessions
PHQ-9 Before22/27
Severe depression
PHQ-9 After5/27
Mild — significant improvement
17 point reduction in depression severity

My wife drove me to the first appointment. I couldn't have driven myself — I hadn't left the house in three weeks. After the second session I walked to the mailbox. After the fourth I called my mother.

James K., Army veteran · PTSD & depression
71%
of patients with PTSD reported clinically significant symptom reduction after a full infusion series
Woman sitting in a sunlit room, looking out a window with a calm, peaceful expression — recovery after ketamine therapy
Priya S.
Chronic pain & depression, 8 sessions
4 min · Her story in her words
"The nurse checked my vitals every twenty minutes. The lights were dimmed exactly right. I had a weighted blanket. I wasn't afraid."
Thomas W. · Fibromyalgia & treatment-resistant depression
Sarah L.
PTSD & Major Depressive Disorder
4 sessions
PHQ-9 Before19/27
Moderately severe
PHQ-9 After3/27
Minimal / Remission
16 point reduction in depression severity

My psychiatrist referred me here after I failed my fifth antidepressant. I was skeptical. I read every study I could find on the drive over. The data was right.

Elena M., research scientist · Treatment-resistant depression
4–6 hrs
is how long many patients describe feeling relief after their first infusion — before the full course is complete
Man sitting outdoors on a bench, sunlight on his face, relaxed and present — symbolizing relief after depression treatment
Marcus B.
Veteran, PTSD & chronic pain · 5 sessions
6 min · 18 months later
"I found the NIH study at 2 a.m. My husband drove me here the next week. That was fourteen months ago. I haven't missed a day of work since my fourth infusion."
Carolyn P. · Chronic pain & depression · Referred by partner
Robert N.
Chronic Pain & Major Depression
6 sessions
PHQ-9 Before24/27
Severe depression
PHQ-9 After7/27
Mild — significant improvement
17 point reduction in depression severity

Three therapists. Six medications. Two hospitalizations. I came here as a last resort. I'm writing this from my garden, which I hadn't touched in two years.

Diane F., retired teacher · Treatment-resistant depression, 18 years
92%
of Infuse patients who completed a full series reported they would recommend ketamine infusion therapy to others in similar situations
Who Comes to Infuse

This treatment is for people who have already tried everything else.

Ketamine is not a first-line treatment. It's what comes after. If that's where you are, you're exactly who we see.

The Professional

You've tried every medication your psychiatrist could prescribe.

You hold a job, a family, a calendar full of obligations. From the outside, everything looks fine. Inside, you've been cycling through SSRIs, SNRIs, and augmentation strategies for years. Your psychiatrist has referred you here. You've read the studies.

Typical profile: 35–55 · 4–8 prior medications tried · Currently functional but not well · Often referred by psychiatrist or therapist

The Veteran

PTSD that won't quiet at night, even when the days are better.

You've done the work. Therapy, medication, the VA programs. Some things helped at the edges. But the hypervigilance, the intrusive memories, the nights — those haven't moved. You found this clinic because someone in your unit mentioned it, or because you finally ran out of other options.

Typical profile: Military or first responder · Combat or trauma exposure · Sleep-disrupted for years · May have chronic pain alongside PTSD

The Chronic Pain Patient

Pain that rewired your mood long before you recognized the depression.

Fibromyalgia, CRPS, neuropathy, post-surgical pain. The physical and emotional have become indistinguishable. Your partner drove you here after reading a NIH study at 2 a.m. You're exhausted in a way that sleep doesn't fix. Ketamine has a dual mechanism — it addresses both.

Typical profile: Fibromyalgia, CRPS, or neuropathic pain · Depression developed secondary to pain · Often referred by pain management specialist

The Infuse Experience

Two hours. A recliner.
A nurse who stays.

The protocol is clinical. The environment is not. We've spent years designing a space where the medicine can work without the ambient stress of a medical setting undermining it.

-30

Arrival & intake

You arrive 30 minutes early. A nurse reviews your vitals, your medications, and your PHQ-9 score from intake. You'll meet the clinician who will stay with you. There's no waiting room smell. The lights are already dimmed.

Soft lighting, quiet, no fluorescent overhead
0:00

The recliner, not the table

You're seated in a recliner, not a hospital bed. A weighted blanket if you want one. An eye mask. Noise-canceling headphones with a curated playlist — or silence. The IV is placed gently. It takes less than two minutes.

Weighted blanket, optional eye mask, curated ambient sound
0:10

The medicine begins

Ketamine is administered over 40-60 minutes at a sub-anesthetic dose. Some patients describe a gentle floating sensation. Others notice colors becoming vivid, or thoughts arriving with unusual clarity. The nurse checks your vitals every 20 minutes throughout.

Dissociative but not frightening — most describe it as peaceful
1:00

The infusion completes

The IV is removed. You remain in the recliner. The clinical team stays with you as the medicine clears. Many patients describe this as the moment the ceiling looks different — softer, somehow more permissive. You're not rushed.

The room feels quieter. Some patients cry. Most don't. Both are fine.
2:00

Recovery & debrief

You sit up when you're ready. The clinician spends 15-20 minutes with you. You eat something light. A family member or trusted person picks you up — you won't drive today. Most patients feel clear enough to return to light activity the following morning.

Tea is available. The lights come up slowly. You leave when you're ready.
A note on the medicine

Ketamine works on the NMDA receptor — a pathway that SSRIs and SNRIs don't touch. This is why it reaches patients who've exhausted conventional antidepressants. It's not a mood stabilizer. It appears to rebuild neural pathways that depression has pruned. The effect can be rapid. The durability depends on the individual.

Medical Screening · HIPAA Compliant

The first step is finding out if you're a candidate.

Our intake screener takes 8 minutes. A clinician reviews every submission within one business day. There's no commitment in answering the questions.

What happens when you click through:

  • A 10-question clinical screener (8 minutes)
  • Review by a licensed clinician within 24 hours
  • A call to discuss fit, timeline, and any questions
  • No commitment required at any stage
See If You're a Candidate

HIPAA-compliant · No credit card · No commitment

Clinical Overview PDF

Not ready to screen yet? Download our clinical overview — dosing protocols, published outcome data, and answers to the questions most patients arrive with.

Ready to find out?

See If You're a Candidate